Publications

This page is a list of publications in reverse chronological order. Please use search or the filters to browse by research areas, publication types, and content types.

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Update Fall 2018

Health Effects Institute
November 2018
Newsletter

In this issue of Update, read about two important new HEI studies underway; a plan to intensively review and publish initial findings on PM2.5 from our “Low Exposure Levels” research program; our search for investigators to conduct new accountability and exposure assessment research; announcement of the 2018 Walter A. Rosenblith New Investigator Award recipient; and more.

Air Quality-by-Genomics Interactions in a Cardiovascular Disease Cohort

William E Kraus
Elizabeth R Hauser
Susanne Breitner
Alexandra Schneider
Akihiko Nishimura
Damian M Craig
Svati H Shah
October 2018
Unpublished Report

This unpublished report describes a three-year study aimed at examining the effects of short-term and long-term air pollution exposure on cardiovascular disease outcomes in a high-risk population, linking biomarker and genomic data to air quality data. Kraus and colleagues at Duke University used previously collected data from CATHGEN, a cohort of approximately 7,000 individuals undergoing coronary artery catheterization in North Carolina between 2001 and 2010.

Use of Real-Time Sensors to Assess Misclassification and to Identify Main Sources Contributing to Peak and Chronic Exposures

Juana Maria Delgado-Saborit
Adobi Okam
Maryam Shehab
Tuan van Vu
September 2018
Unpublished report

This unpublished report describes a three-year study aimed at evaluating exposures to air pollutants from traffic and indoor sources. The study followed a panel of participants who lived close to or further away from busy roads and had either gas or electric stoves. The investigators measured the participants’ exposures indoors and outdoors, as well as their personal exposures in various microenvironments, using real-time pollutant sensors that were fairly novel at the time.

Update Summer 2018

Health Effects Institute
August 2018
Newsletter

In this issue of Update, read about HEI’s recent testimony on the U.S. Environmental Protection Agency’s proposed “Strengthening Transparency in Regulatory Science” rule; a recap of the 2018 Annual Conference in Chicago, Illinois; a new HEI Communication assessing the evidence on health effects from household air pollution; progress in the new Energy Research Program; and more.

Household Air Pollution and Noncommunicable Disease

HEI Household Air Pollution Working Group
July 2018
Communication 18

Communication 18 provides a critical assessment of the state of the science examining the linkages between household air pollution formed by the burning of solid fuels and noncommunicable diseases. The report updates previous systematic reviews with the most recent studies. It answers fundamental questions on the scientific basis for estimating health burden and what the evidence suggests about the exposure reductions necessary to achieve improved health outcomes. The Summary for Policy Makers, based on Communication 18, presents the main conclusions about exposures to household air pollution and about its contribution to noncommunicable diseases globally.

Evaluation of Alternative Sensor-based Exposure Assessment Methods

Edmond Seto
Elena Austin
Graeme Carvlin
Jeffry Shirai
Alan Hubbard
Katherine Hammond
Ying-Ying Meng
Michael Jerrett
Ronald Cohen
July 2018
Unpublished report

This unpublished report describes a one-year study aimed at evaluating low-cost sensors in a dense network of near-road monitoring sites in the San Francisco Bay area. The overarching goal was to evaluate the ability of low-cost sensors to characterize traffic-related air pollution. The specific aims were to (1) colocate and compare low-cost sensors with regulatory instruments and (2) evaluate the ability of the low-cost sensors to characterize variations in traffic-related air pollution that are associated with different traffic counts. The topic of the study is of interest since the development and use of low-cost air pollution sensors are progressing rapidly, and these sensors have the potential to transform the way air pollution research is conducted.

HEI Investigators' Guide. Preparing the Final Report

Health Effects Institute
June 2018
Guide for Authors

The Investigators' Guide contains important information for HEI-funded investigators who are getting ready to write the Final Report for their study. The Guide introduces HEI's review, editing, and publication process and lists requirements for submission of the report. The Guide also contains detailed instructions on reference and text styles, tables and illustrations, and submission of electronic art.

Update Spring 2018

Health Effects Institute
May 2018
Newsletter

This issue of Update highlights the report of a major new HEI study, Impacts of Regulations on Air Quality and Emergency Department Visits in the Atlanta Metropolitan Area, 1999–2013, led by Armistead (Ted) Russell of the Georgia Institute of Technology; the public release of data from HEI’s major ozone study, the Multicenter Ozone Study in oldEr Subjects (MOSES); a new HEI panel conducting a literature review on the health effects of traffic-related air pollution; the publication of State of Global Air 2018; appointment of two new members to the Institute’s Board of Directors; a new chair of the HEI Research Committee; and more.

Developing Multipollutant Exposure Indicators of Traffic Pollution: The Dorm Room Inhalation to Vehicle Emissions (DRIVE) Study

Jeremy A Sarnat
Armistead (Ted) G Russell
Donghai Liang
Jennifer L Moutinho
Rachel Golan
Rodney J Weber
Dong Gao
Stephanie Ebelt Sarnat
Howard H Chang
Roby Greenwald
Tianwei Yu
April 2018
Research Report 196

Research Report 196, Developing Multipollutant Exposure Indicators of Traffic Pollution: The Dorm Room Inhalation to Vehicle Emissions (DRIVE) Study, describes a study by Dr. Jeremy A. Sarnat that evaluated single- and multipollutant metrics of exposure to traffic-related air pollutants near and farther away from a major highway in Atlanta, as well as biological markers in a panel of students.

Impacts of Regulations on Air Quality and Emergency Department Visits in the Atlanta Metropolitan Area, 1999–2013

Armistead (Ted) G Russell
Paige E Tolbert
Lucas RF Henneman
Joseph Abrams
Cong Liu
Mitchel Klein
James A Mulholland
Stefanie Ebelt Sarnat
Yongtao Hu
Howard H Chang
Talat Odman
Matthew J Strickland
Huizhong Shen
Abiola Lawal
April 2018
Research Report 195

Research Report 195 describes a study led by Ted Russell at the Georgia Institute of Technology as part of HEI’s Accountability Research Program. Dr. Russell and colleagues examined the extent to which regulations targeting power plants and mobile sources in the Atlanta area were effective in improving air quality and ultimately reducing cardiorespiratory emergency department visits.

Update Winter 2018

Health Effects Institute
February 2018
Newsletter

This issue of Update highlights a major new HEI Special Report, Burden of Disease Attributable to Major Air Pollution Sources in India; three studies now underway to assess exposure to and health effects of traffic-related air pollution; and a new HEI Research Report on “Street Canyon” air pollution exposure modeling. Also in this edition, read about our upcoming Annual Conference; a recent meeting of diverse stakeholders hosted by HEI’s Energy Research Program; President Dan Greenbaum lending expertise to a National Academies “Grand Challenges” project; and more.

A Dynamic Three-Dimensional Air Pollution Exposure Model for Hong Kong

Benjamin Barratt
Martha Lee
Paulina Wong
Robert Tang
Tsz Him Tsui
Wei Cheng
Yang Yang
Poh-Chin Lai
Linwei Tian
Thuan-Quoc Thach
Ryan Allen
Michael Brauer
February 2018
Research Report 194

HEI’s Research Report 194 describes a study led by Benjamin Barratt of King’s College London, United Kingdom, that developed a dynamic three-dimensional land-use regression model for Hong Kong and used it to estimate exposure to traffic-related air pollution.

Annual Report 2017

Health Effects Institute
February 2018
Annual Report 2017

The 2017 Annual Report, A Voice for Accountability, describes the HEI model for delivering high-quality, impartial, and relevant science to inform public policy decisions about air quality and public health.

Burden of Disease Attributable to Major Air Pollution Sources in India

GBD MAPS Working Group
January 2018
Special Report 21

Special Report 21, Burden of Disease Attributable to Major Air Pollution Sources in India, provides the first comprehensive analysis of the levels of fine particulate matter air pollution in India by source and their impact on health. Household burning emissions (contributing to outdoor air) and coal combustion are the single largest sources of air pollution-related health impact. Emissions from agricultural burning, anthropogenic dusts, transport, other diesel, and brick kilns also contribute significantly.

Update Fall 2017

Health Effects Institute
October 2017
Newsletter

In this issue of HEI Update, read about the new ways HEI is making study data accessible; a literature review that HEI will soon initiate on the effects of exposure to traffic-related air pollution; two new members of the HEI Review Committee; and a newly published summary of an HEI expert workshop on the effects of fuel composition on particulate matter emissions.

Particulate Air Pollutants, Brain Structure, and Neurocognitive Disorders in Older Women

Jiu-Chiuan Chen
Xinhui Wang
Marc Serre
Steven Cen
Meredith Franklin
Mark Espeland
October 2017
Research Report 193

Research Report 193 describes a novel study by Jiu-Chiuan Chen and colleagues examining possible associations between long-term exposure to ambient particulate matter (PM) and changes in the brains of older women in the United States. The study focused on brain volumes and neurocognitive outcomes, specifically mild cognitive impairment and dementia. Dr. Chen used neuroimaging and cognitive outcome data from women enrolled in the Women’s Health Initiative Memory Study and estimated their exposure to ambient PM2.5 and to diesel PM.

Update Summer 2017

Health Effects Institute
August 2017
Newsletter

In this issue of HEI Update, read about the Haagen-Smit Clean Air Leadership Award given to HEI President Dan Greenbaum by the California Air Resources Board, the two 2017 recipients of HEI’s Walter A. Rosenblith New Investigator Award, and the progress of HEI studies examining potential health effects at low levels of air pollution. Also in this issue is a recap of HEI’s recent Annual Conference in Alexandria, Virginia.

Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes

Mark W Frampton
John R Balmes
Philip A Bromberg
Paul Stark
Mehrdad Arjomandi
Milan J Hazucha
David Q Rich
Danielle Hollenbeck-Pringle
Nicholas Dagincourt
Neil Alexis
Peter Ganz
Wojciech Zareba
Maria G Costantini
June 2017
Research Report 192 Part 1

HEI Research Report 192 describes a multicenter study by John Balmes at the University of California–San Francisco, Phil Bromberg at the University of North Carolina–Chapel Hill, and Mark Frampton at the University of Rochester, New York. The study was designed to test whether ozone has short-term cardiovascular effects at present-day ambient levels. It evaluated respiratory and cardiovascular outcomes in 87 healthy participants (60 years old on average) who were exposed to 0, 70, or 120 ppb ozone for 3 hours while exercising moderately.

Update Spring 2017

Health Effects Institute
June 2017
Newsletter

In this issue of Update, read about HEI’s forthcoming publication of a major report, Multicenter Ozone Study in Older Subjects; the briefing of key legislators and stakeholders on HEI’s Accountability Research Program; and a forthcoming study examining potential links between air pollution and dementia in older women. This issue also highlights worldwide media coverage of HEI’s State of Global Air Report 2017.

Protective Role of Eosinophils and Tumor Necrosis Factor-α after Ozone Inhalation

Allison D Fryer
David B Jacoby
Sarah A Wicher
March 2017
Research Report 191

Research Report 191 describes a study by Allison Fryer and colleagues that addressed how exposure to ozone affects the immune and physiological responses in guinea pigs. In her study, Dr. Fryer focused on eosinophils, white blood cells that play an important role in inflammation, allergies, and allergic asthma, and can modify the airway response to ozone inhalation. This study tested a novel hypothesis: that allergic guinea pigs react differently to ozone than normal animals because of newly formed eosinophils that migrate from bone marrow to the lungs.

Update Winter 2017

Health Effects Institute
February 2017
Newsletter

In this issue of Update, read about HEI’s new “State of Global Air” annual report and website and our upcoming Annual Conference in Alexandria, Virginia (see the preliminary program). Also read about the recipient of the 2016 Walter A. Rosenblith New Investigator Award, the appointment of a new member to HEI’s Board of Directors, and HEI "Communicating the Science” at meetings in the U.S. and abroad.

Annual Report

Health Effects Institute
January 2017
Annual Report

The 2016 Annual Report, Trusted Science for Decisions, describes HEI’s partnership with industry, government, scientists, and the environmental community to provide high-quality, impartial, and relevant science to inform public policy decisions about air quality and public health. Included is a description of HEI’s rigorous approach to science and the many ways diverse stakeholders in the United States and worldwide put the research findings to use.

The Effects of Policy-Driven Air Quality Improvements on Children’s Respiratory Health

Frank Gilliland
Edward L Avol
Rob McConnell
Kiros T Berhane
W James Gauderman
Fred W Lurmann
Robert Urman
Roger Chang
Edward B Rappaport
Stephen Howland
January 2017
Research Report 190

Research Report 190 describes a study by Frank Gilliland and colleagues that was funded under HEI’s Accountability research program. The investigators collected air quality data and lung function and respiratory symptoms in three cohorts of children who participated in the Children’s Health Study in Southern California. During the 20-year study period, nearly 20 major policy actions were implemented to reduce pollution from transportation and other sources. Gilliland and colleagues evaluated whether the improved air quality was associated with improved lung function and respiratory symptoms in these children.

Update Fall 2016

Health Effects Institute
October 2016
Newsletter

This issue of Update reports on a new study that explored the impact of Southern California air-quality regulations on children’s health; launch of the redesigned HEI Web site; new HEI Review Committee member Jennifer Peel; upcoming requests for applications; the sharing of HEI science at major Asian and European conferences; and HEI in the News.

Ambient Air Pollution and Adverse Pregnancy Outcomes in Wuhan, China

Zhengmin Qian
Bin Zhang
Shengwen Liang
Jing Wang
Shaoping Yang
Ke Hu
Edwin Trevathan
Rong Yang
Qijie Li
Louise H Flick
Ronghua Hu
Zhen Huang
Yimin Zhang
Shixiang Hu
Jing Wang
Longjiao Shen
Yuan Lu
Hui Peng
Yuzhen Yu
Li Yang
Wei Chen
Wenjin Liu
Wei Zhang
September 2016
Research Report 189

HEI Research Report 189 describes a study by Dr. Zhengmin Qian conducted in Wuhan, the capital city of Hubei province in China. Wuhan experiences temperature extremes and generally has higher air pollution levels than those seen in the United States and Europe. Dr. Qian examined whether increased exposures to air pollutants (particulate matter, sulfur dioxide, nitrogen dioxide, carbon monoxide, and ozone) during vulnerable pregnancy periods were associated with increased rates of preterm birth, low birth weight, or intrauterine growth retardation, using both a cohort and nested case-control design.