Publications

Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes

Mark W Frampton
John R Balmes
Philip A Bromberg
Paul Stark
Mehrdad Arjomandi
Milan J Hazucha
David Q Rich
Danielle Hollenbeck-Pringle
Nicholas Dagincourt
Neil Alexis
Peter Ganz
Wojciech Zareba
Maria G Costantini
June 2017
Research Report 192 Part 1

HEI Research Report 192 describes a multicenter study by John Balmes at the University of California–San Francisco, Phil Bromberg at the University of North Carolina–Chapel Hill, and Mark Frampton at the University of Rochester, New York. The study was designed to test whether ozone has short-term cardiovascular effects at present-day ambient levels. It evaluated respiratory and cardiovascular outcomes in 87 healthy participants (60 years old on average) who were exposed to 0, 70, or 120 ppb ozone for 3 hours while exercising moderately.

Update Spring 2017

Health Effects Institute
June 2017
Newsletter

In this issue of Update, read about HEI’s forthcoming publication of a major report, Multicenter Ozone Study in Older Subjects; the briefing of key legislators and stakeholders on HEI’s Accountability Research Program; and a forthcoming study examining potential links between air pollution and dementia in older women. This issue also highlights worldwide media coverage of HEI’s State of Global Air Report 2017.

Protective Role of Eosinophils and Tumor Necrosis Factor-α after Ozone Inhalation

Allison D Fryer
David B Jacoby
Sarah A Wicher
March 2017
Research Report 191

Research Report 191 describes a study by Allison Fryer and colleagues that addressed how exposure to ozone affects the immune and physiological responses in guinea pigs. In her study, Dr. Fryer focused on eosinophils, white blood cells that play an important role in inflammation, allergies, and allergic asthma, and can modify the airway response to ozone inhalation. This study tested a novel hypothesis: that allergic guinea pigs react differently to ozone than normal animals because of newly formed eosinophils that migrate from bone marrow to the lungs.

Update Winter 2017

Health Effects Institute
February 2017
Newsletter

In this issue of Update, read about HEI’s new “State of Global Air” annual report and website and our upcoming Annual Conference in Alexandria, Virginia (see the preliminary program). Also read about the recipient of the 2016 Walter A. Rosenblith New Investigator Award, the appointment of a new member to HEI’s Board of Directors, and HEI "Communicating the Science” at meetings in the U.S. and abroad.