Publications

Protective Role of Eosinophils and Tumor Necrosis Factor-α after Ozone Inhalation

Allison D Fryer
David B Jacoby
Sarah A Wicher
March 2017
Research Report 191

Research Report 191 describes a study by Allison Fryer and colleagues that addressed how exposure to ozone affects the immune and physiological responses in guinea pigs. In her study, Dr. Fryer focused on eosinophils, white blood cells that play an important role in inflammation, allergies, and allergic asthma, and can modify the airway response to ozone inhalation. This study tested a novel hypothesis: that allergic guinea pigs react differently to ozone than normal animals because of newly formed eosinophils that migrate from bone marrow to the lungs.

Update Winter 2017

Health Effects Institute
February 2017
Newsletter

In this issue of Update, read about HEI’s new “State of Global Air” annual report and website and our upcoming Annual Conference in Alexandria, Virginia (see the preliminary program). Also read about the recipient of the 2016 Walter A. Rosenblith New Investigator Award, the appointment of a new member to HEI’s Board of Directors, and HEI "Communicating the Science” at meetings in the U.S. and abroad.

Annual Report

Health Effects Institute
January 2017
Annual Report

The 2016 Annual Report, Trusted Science for Decisions, describes HEI’s partnership with industry, government, scientists, and the environmental community to provide high-quality, impartial, and relevant science to inform public policy decisions about air quality and public health. Included is a description of HEI’s rigorous approach to science and the many ways diverse stakeholders in the United States and worldwide put the research findings to use.

The Effects of Policy-Driven Air Quality Improvements on Children’s Respiratory Health

Frank Gilliland
Edward L Avol
Rob McConnell
Kiros T Berhane
W James Gauderman
Fred W Lurmann
Robert Urman
Roger Chang
Edward B Rappaport
Stephen Howland
January 2017
Research Report 190

Research Report 190 describes a study by Frank Gilliland and colleagues that was funded under HEI’s Accountability research program. The investigators collected air quality data and lung function and respiratory symptoms in three cohorts of children who participated in the Children’s Health Study in Southern California. During the 20-year study period, nearly 20 major policy actions were implemented to reduce pollution from transportation and other sources. Gilliland and colleagues evaluated whether the improved air quality was associated with improved lung function and respiratory symptoms in these children.