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Biological Methods

This page has a list of publications and news articles related to Innovative Strategies - Biological Methods. Find more information on Innovation in HEI's research programs.

Research Report 215
Manabu Shiraiwa
Ting Fang
Jinlai Wei
Pascale SJ Lakey
Brian CH Hwang
Kasey C Edwards
et al.
2023

This report presents the findings of a study led by Manabu Shiraiwa of the University of California, Irvine, a recipient of HEI’s Walter A. Rosenblith New Investigator Award. Shiraiwa and colleagues evaluated the mechanisms of aerosol-induced reactive oxygen species formation by two pathways in the respiratory tract: by chemical reactions  and by immune cells called macrophages.

Research Report 204
Kymberly Gowdy
Brita Kilburg-Basnyat
Myles X Hodge
Sky W Reece
Valery Yermalitsky
Sean S Davies
Jonathan Manke
Michael L Armstrong
Nichole Reisdorph
Robert M Tighe
S Raza Shaikh
2021

Research Report 204 presents a study led by Dr. Kymberly Gowdy of East Carolina University (now at Ohio State University) and colleagues in which they evaluated how acute exposure of mice to ozone affects initiation and resolution of the inflammatory response in the lung.

Newsletter
Health Effects Institute
2020

In this issue of Update, read about two new HEI Board members; HEI’s formal response to EPA’s proposed transparency rule; a new chair for our Review Committee; HEI’s actions to promote diversity; a recently published Walter A. Rosenblith New Investigator report on novel techniques to study VOC–ozone effects… and more!

Research Report 201
Lydia M Contreras
Juan C Gonzalez-Rivera
Kevin C Baldridge
Dongyu S Wang
Jamie CL Chuvalo-Abraham
Lea Hildebrandt Ruiz
2020

Research Report 201 presents a study led by Dr. Lydia Contreras at the University of Texas, Austin, who is a recipient of HEI’s Walter A. Rosenblith New Investigator Award. Dr. Contreras and colleagues evaluated how exposure of lung cells to volatile organic compounds plus ozone affects oxidation of ribonucleic acid, a key component of cells. The study aimed to improve understanding of the biological mechanisms by which air pollutants can cause effects in human health, thereby expanding our knowledge of potential causal links between exposure and health.

This newsletter reports on the approval of new HEI studies to examine potential health effects of low-level pollution; the completion of a review of diesel exhaust studies (Special Report 19) by an HEI-appointed panel; and WHO's plans to update global air quality guidelines. In addition, it announces the publication of an HEI report taking a closer look at exposure to PM2.5 and its composition and a report evaluating rapid heart rhythm changes after exposure to PM. HEI also announces the recipient of the 2015 Walter A. Rosenblith New Investigator Award and the appointment of three new HEI Research Committee members.

Contents: HEI's Strategic Plan for 2015–2020 Now Under Way;  Greenbaum Chairs NRC Review of U.S. Climate, Health Assessment; O'Keefe Closes Out Successful Run on Key Air Advisory Committee; Communicating Results - HEI Science Highlighted at EPA Workshops HEI in the News - Wide Audience for ACES Findings; Novel Statistical Methods for Studying Pollutant Mixtures; Journal Spotlights NPACT Studies; Eyes on the Future - HEI Sponsors Meet with Research Committee to Discuss the Path Forward;  Walter A. Rosenblith New Investigator Award Announced

Contents: Setting a Course for 2020: The HEI Strategic Plan; RFA Seeks New Epidemiologic Studies; HEI Launches New International Project // Group of Experts Will Estimate Global Burden of Disease from Specific Major Air Pollution Sources; Communicating Results of Research; How PM May Affect Epithelial Cell Differentiation; Progress on Major Ozone Study; Panel Tours Gas Well Sites

Contents: Greenbaum Testifies on "Producing Credible Science for Decisions"; New HEI Health Effects Study of Modern Diesel Engine Emissions; Health Outcomes and Biomarkers Studies Approved; Multicity Study in Latin America; Air Pollution and Children's Health in Vietnam; HEI in the News; Communication 17: ACES Exposure Atmosphere; Annual Report Now Available; New Global Burden of Disease Estimates; HEI Investigator Wins Haagen-Smit Prize; Workshop on Assessing Exposure to Pollution from Traffic; IARC Review of Diesel and Gasoline Exhaust