This unpublished report describes a three-year study aimed at examining the effects of short-term and long-term air pollution exposure on cardiovascular disease outcomes in a high-risk population, linking biomarker and genomic data to air quality data. Kraus and colleagues at Duke University used previously collected data from CATHGEN, a cohort of approximately 7,000 individuals undergoing coronary artery catheterization in North Carolina between 2001 and 2010.