Diesel Exhaust

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Examining air pollution and neurocognitive effects in older women

October 12, 2017

HEI has published Research Report 193, which describes a novel study of older women in the United States led by Jiu-Chiuan Chen of the University of Southern California. The investigators examined the possible association between long-term exposure to ambient particulate matter and changes in brain volumes and in neurocognitive outcomes, specifically mild cognitive impairment and dementia.

Research Report 193
Jiu-Chiuan Chen
Xinhui Wang
Marc Serre
Steven Cen
Meredith Franklin
Mark Espeland
October 2017

Research Report 193 describes a novel study by Jiu-Chiuan Chen and colleagues examining possible associations between long-term exposure to ambient particulate matter (PM) and changes in the brains of older women in the United States. The study focused on brain volumes and neurocognitive outcomes, specifically mild cognitive impairment and dementia. Dr. Chen used neuroimaging and cognitive outcome data from women enrolled in the Women’s Health Initiative Memory Study and estimated their exposure to ambient PM2.5 and to diesel PM.

Communication - ACES
Health Effects Institute
December 2015

This Executive Summary of the Advanced Collaborative Emissions Study (ACES) summarizes the main findings of emissions and health testing of new-technology heavy-duty diesel engines capable of meeting US 2007/2010 and EURO VI/6 diesel emissions standards. The results demonstrated the dramatic improvements in emissions and the absence of any significant health effects (especially cancer). ACES was the most comprehensive examination done to date of engines meeting the US 2007 and 2010 on-road standards.

Special Report 19
HEI Diesel Epidemiology Panel
November 2015

Special Report 19 contains the intensive review and analysis of the newest studies of mine and truck workers exposed to older diesel engine exhaust conducted by an Expert Panel appointed by the HEI Board of Directors. In its report, HEI's Diesel Epidemiology Panel concluded that the studies are well prepared and are useful for applying the data to calculate the cancer risk due to exposure to diesel exhaust.

This newsletter reports on the approval of new HEI studies to examine potential health effects of low-level pollution; the completion of a review of diesel exhaust studies (Special Report 19) by an HEI-appointed panel; and WHO's plans to update global air quality guidelines. In addition, it announces the publication of an HEI report taking a closer look at exposure to PM2.5 and its composition and a report evaluating rapid heart rhythm changes after exposure to PM. HEI also announces the recipient of the 2015 Walter A. Rosenblith New Investigator Award and the appointment of three new HEI Research Committee members.

Newsletter
Health Effects Institute
August 2015

This issue reports on the publication of an Executive Summary highlighting ACES new-technology diesel results, which describes significant improvements in new diesel engines; a conference showcasing HEI science and emerging research opportunities; interest worldwide in ACES findings; how HEI staff are communicating results; the status of the oil and gas research agenda being drafted by HEI; and the status of the MOSES testing of ozone study subjects.

Newsletter
Health Effects Institute
February 2015

Contents: Major Report on Newest Diesel Engines - No Evidence of Lung Cancer in Rats after Lifetime Exposure to New-Technology Diesel Exhaust; Sign Up Now for HEI's Annual Conference 2015 in Philadelphia in May; Nominations for Committee Membership Invited; Progress on Strategic Research Plan for Oil and Gas; Better Air Quality Meeting in Sri Lanka

Research Report 184
Jacob D McDonald
Jeffrey C Bemis
Lance M Hallberg
Daniel J Conklin
January 2015

This report describes four studies conducted as a single phase (Phase 3B) of HEI's Advanced Collaborative Emissions Study (ACES) program, which was designed to evaluate the emissions and health changes resulting from substantially improved diesel engines required under the U.S. EPA 2007–2010 Heavy Duty Diesel Rule. These studies were conducted by Drs. Jacob D. McDonald of the Lovelace Respiratory Research Institute, Albuquerque, New Mexico, Jeffrey C. Bemis of Litron Laboratories, Rochester, New York, Lance M. Hallberg of the University of Texas Medical Branch, Galveston, Texas, and Daniel J. Conklin, University of Louisville, Kentucky.

Newsletter
Health Effects Institute
May 2014

Contents: HEI Research Committee Welcomes a New Epidemiologist; Ultrafine Particles Study Focuses on School Buses; New Initiative Addresses Unconventional Oil and Gas Development; A Growing Audience for HEI's Web Site; Sponsors, Research Committee Meet in Boston;  Assessing Diesel Epidemiology Studies; Walter A. Rosenblith New Investigator Award

Newsletter
Health Effects Institute
February 2014

Contents: ACES Phase 2 Study Shows Dramatic Reductions in Emissions from Newer Diesel Engines; Annual Conference in D.C. Area Will Spotlight Science to Inform the Future; HEI Hosts Diesel Epidemiology Workshop; Making Data on Air Pollution and Health Accessible;  New Funding Opportunities: Traffic Related Exposure Studies / HEI Seeks Research on Non-Tailpipe and Tailpipe Emissions Near Urban Roads and in Tunnels; Window on Tomorrow: Building the HEI Strategic Plan 2015–2020