Air Pollution

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Air Pollution and Adverse Reproductive Health Outcomes

August 3, 2016

HEI Research Report 188 analyzes associations between increases in various air pollution exposure metrics and increased risks of preterm birth. Jun Wu was funded under HEI's Walter A. Rosenblith New Investigator Award to conduct a comprehensive nested, case-control study of air pollution and adverse birth and pregnancy outcomes, using birth certificate data collected in California from 2001 to 2008. 

Research Report 188
Jun Wu
Olivier Laurent
Lianfa Li
Jianlin Hu
Michael Kleeman
July 2016

HEI Research Report 188 analyzes associations between increases in various air pollution exposure metrics and increased risks of preterm birth. Jun Wu was funded under HEI's Walter A. Rosenblith New Investigator Award to conduct a comprehensive nested, case-control study of air pollution and adverse birth and pregnancy outcomes, using birth certificate data collected in California from 2001 to 2008. 

Summer 2016 Update now available

July 26, 2016

The Summer 2016 Update features a new report on air pollution effects on birth and pregnancy outcomes, and the presentation of Global Burden of Disease – Major Air Pollution Sources (GBD MAPS) results at a major Chinese air pollution meeting. Also read a recap of the Annual Conference in Denver and HEI briefings with policy experts, regulators, and advisory committees. 

Unpublished report
Richard E Peltier
Whitney Huynh
Pallavi Pant
Massimiliano Mascelloni
June 2016

This unpublished research report describes a two-year study aimed at building and testing a method for the semi-continuous measurement of reactive oxidant species (ROS) generated by particulate matter in a cellular assay. The assay relied on the use of a compound that turns into a fluorescent product upon reaction with ROS generated in the cells.

Research Report 187
Corwin M. Zigler
Chanmin Kim
Christine Choirat
John Barrett Hansen
Yun Wang
Lauren Hund
Jonathan Samet
Gary King
Francesca Dominici
May 2016

HEI Research Report 187 was funded as part of HEI’s Accountability research program, aimed at understanding whether actions to improve air quality have resulted in improved health outcomes. Corwin M. Zigler and his colleagues used existing and newly developed statistical methods to assess whether an intervention was causally related to changes in pollutant levels or health outcomes, and applied their methods in two well-developed case studies: effects of air quality interventions to reduce PM10 concentrations in nonattainment areas and the impact of installation of scrubber technologies on emissions from coal-fired power plants.

Research Report 186
David Q. Rich
Annette Peters
Alexandra Schneider
Wojciech Zareba
Susanne Breitner
David Oakes
Jelani Wiltshire
Cathleen Kane
Mark W Frampton
Regina Hampel
Philip K Hopke
Josef Cyrys
Mark J Utell
May 2016

Using data from four previously completed studies (two panel studies and two controlled-exposure studies), David Rich and Annette Peters and their teams investigated potential mechanisms behind the effects of short-term exposure to PM2.5 and ultrafine particles on changes in cardiac rhythm, including heart rate variability and other ECG parameters.

"Direct" Approach Evaluates Air Quality Interventions

May 31, 2016

HEI Research Report 187, Causal Inference Methods for Estimating Long-Term Health Effects of Air Quality Regulations, was funded as part of HEI’s Accountability research program, aimed at understanding whether actions to improve air quality have resulted in improved health outcomes.

This newsletter reports on a third study under way in Europe to complete the comprehensive HEI effort to examine the potential health effects of air pollution at low levels; HEI's new research program focusing on the health effects of exposure to traffic-related pollution; and the GBD MAPS team's presentation of preliminary data on coal’s impact on health in China. In addition, it covers the publication of two new research reports covering novel statistical methods for studying pollutant mixtures and a “direct” approach evaluating the impact of air quality interventions through “causal inference” methods, as well as the retirement of HEI's Aaron Cohen, a strategy session held with HEI's sponsors, and HEI in the news.

Spring 2016 Update now available

May 18, 2016

The Spring 2016 newsletter reports on a third study under way in Europe to complete the comprehensive HEI effort to examine the potential health effects of air pollution at low levels; HEI's new research program focusing on the health effects of exposure to traffic-related pollution; and the GBD MAPS team's presentation of preliminary data on coal’s impact on health in China, and more. 

Research Report 183, Part III
John Molitor
Eric Coker
Michael Jerrett
Beate Ritz
Arthur Li
April 2016

This report is Part 3 of HEI Research Report 183, Development of Statistical Methods for Multipollutant Research. It describes a study to develop and apply statistical methods to analyze the effects of multipollutant exposures on health, expanding beyond the two-pollutant approaches used in many studies to date. HEI funded three innovative studies in recent years to improve the tools for analyzing complex multipollutant exposures. In this last report from these studies, John Molitor and colleagues describe a Bayesian framework to identify spatial clusters of air pollution exposures — and other covariates such as socioeconomic status — and estimated pregnancy outcomes associated with those clusters, using a data set for Los Angeles county.