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Air Quality-by-Genomics Interactions in a Cardiovascular Disease Cohort

William E Kraus
Elizabeth R Hauser
Susanne Breitner
Alexandra Schneider
Akihiko Nishimura
Damian M Craig
Svati H Shah
October 2018
Unpublished Report

This unpublished report describes a three-year study aimed at examining the effects of short-term and long-term air pollution exposure on cardiovascular disease outcomes in a high-risk population, linking biomarker and genomic data to air quality data. Kraus and colleagues at Duke University used previously collected data from CATHGEN, a cohort of approximately 7,000 individuals undergoing coronary artery catheterization in North Carolina between 2001 and 2010.

Use of Real-Time Sensors to Assess Misclassification and to Identify Main Sources Contributing to Peak and Chronic Exposures

Juana Maria Delgado-Saborit
Adobi Okam
Maryam Shehab
Tuan van Vu
September 2018
Unpublished report

This unpublished report describes a three-year study aimed at evaluating exposures to air pollutants from traffic and indoor sources. The study followed a panel of participants who lived close to or further away from busy roads and had either gas or electric stoves. The investigators measured the participants’ exposures indoors and outdoors, as well as their personal exposures in various microenvironments, using real-time pollutant sensors that were fairly novel at the time.

Update Summer 2018

Health Effects Institute
August 2018

In this issue of Update, read about HEI’s recent testimony on the U.S. Environmental Protection Agency’s proposed “Strengthening Transparency in Regulatory Science” rule; a recap of the 2018 Annual Conference in Chicago, Illinois; a new HEI Communication assessing the evidence on health effects from household air pollution; progress in the new Energy Research Program; and more.

Household Air Pollution and Noncommunicable Disease

HEI Household Air Pollution Working Group
July 2018
Communication 18

Communication 18 provides a critical assessment of the state of the science examining the linkages between household air pollution formed by the burning of solid fuels and noncommunicable diseases. The report updates previous systematic reviews with the most recent studies. It answers fundamental questions on the scientific basis for estimating health burden and what the evidence suggests about the exposure reductions necessary to achieve improved health outcomes. The Summary for Policy Makers, based on Communication 18, presents the main conclusions about exposures to household air pollution and about its contribution to noncommunicable diseases globally.