New SoGA 2025 Report

The report covers global air quality and health impacts, including data on noncommunicable diseases.
Learn More

Ozone & Oxidants

This page has a list of publications and news articles related to Air Pollution - Ozone and Oxidants. Find more information about our research on Air Pollution.

Consequences of Prolonged Inhalation of Ozone on F344/N Rats: Collaborative Studies. Part XIII: A Comparison of Changes in the Tracheobronchial Epithelium and Pulmonary Acinus in Male Rats at 3 and 20 Months

Research Report 65-XIII
Kent E Pinkerton
Barbara L Weller
Margaret G Ménache
Charles G Plopper
1998
Topics: 
Ozone & Oxidants

Ozone, a common outdoor air pollutant, is a highly reactive gas and a major component of smog. A public health concern is that prolonged exposure to ozone might damage the airways and contribute to the development of noncancerous respiratory diseases. To examine this issue, the Health Effects Institute collaborated with the NTP to provide HEI-funded investigators access to animals that underwent the same rigorously controlled ozone exposure and quality assurance processes along with the animals used for NTP studies. One of the NTP/HEI investigator groups, Dr.

Read more >

Acute Effects of Ambient Ozone on Asthmatic, Wheezy, and Healthy Children

Research Report 82
Edward L Avol
William Navidi
Edward B Rappaport
John M Peters
1998
Topics: 
Ozone & Oxidants

Dr. John Peters and colleagues of the University of Southern California School of Medicine compared the lung function, respiratory symptoms, activity levels, and bronchodilator use of 10- to 12-year-old healthy, asthmatic, and wheezy children. They conducted the study in Southern California during mid-spring (when ozone levels were expected to be low) and late summer (when ozone levels were expected to be high).

Read more >

Methods Development for Epidemiologic Investigations of the Health Effects of Prolonged Ozone Exposure

Research Report 81
Ira B Tager
Patrick L Kinney
1998
Topics: 
Air Pollution
Ozone & Oxidants
Innovation
Exposure Methods

Dr. Ira Tager and colleagues at the University of California at Berkeley (UCB), and Dr. Patrick Kinney and colleagues at the School of Public Health, Columbia University objectives were to develop new methods for estimating an individual's past exposure to ozone.

Read more >

Improvement of a Respiratory Ozone Analyzer

Research Report 79
James S Ultman
Abdellaziz Ben-Jebria
Craig S MacDougall
Marc L Rigas
1997
Topics: 
Ozone & Oxidants
Biological Methods

Dr. Ultman and his colleagues at Pennsylvania State University redesigned their first-generation analyzer that measures the dose of inhaled ozone to reduce electronic noise (interference) and improve the signal's stability. To do so, they adjusted each parameter that influenced the analyzer's performance: the flow of the air sample into the instrument, the pressure in the chamber where the air sample and the reactant gas mixed, the relative amounts of the reactant gas and air sample, and electronic variables (frequency and voltage).

Read more >

Effects of Ozone on Normal and Potentially Sensitive Human Subjects

Research Report 78
John R Balmes
Mark W Frampton
1997
Topics: 
Ozone & Oxidants

Dr. John Balmes and colleagues of the University of California, San Francisco, and Dr. Mark Frampton and associates of the University of Rochester characterized ozone-induced responses in two different study populations: normal and asthmatic men and women in the Balmes study (Part I), and male and female nonsmokers and smokers in the Frampton study (Part II). The investigators addressed three issues: (1) Is an individual's reactivity to inhaled methacholine related to changes in lung function after exposure to ozone? (2) What is the relation between ozone-induced airway inflammation and changes in lung function? and (3) Do the changes in lung function and markers of inflammation in response to ozone exposure differ between normal people and people with asthma?

Read more >

Consequences of Prolonged Inhalation of Ozone on F344/N Rats: Collaborative Studies. Part XII: Atrophy of Bone in Nasal Turbinates

Research Report 65-XII
Jack R Harkema
Paul J Catalano
Jon Hotchkiss
1997
Topics: 
Ozone & Oxidants

Ozone is a highly reactive gas that is a pervasive air pollutant at ground level. It is a major component of urban smog, forming when emissions from mobile and industrial sources interact with sunlight. The Health Effects Institute collaborated with the NTP to provide eight HEI-funded investigators access to animals that underwent the same rigorously controlled ozone inhalation protocol and quality assurance processes along with the NTP animals. HEI funded this follow-on study to allow Dr.

Read more >