Diesel Exhaust

This page has a list of publications and news articles related to Air Pollution - Diesel Exhaust. Find more information about our research on Air Pollution.

Research Report 178
Sverre Vedal
Matthew J Campen
Jacob D McDonald
Joel D Kaufman
Timothy V Larson
Paul D Sampson
Lianne Sheppard
Christopher D Simpson
Adam A Szpiro
October 2013

This report describes the results of two cohort studies of long-term effects of PM components on subclinical and clinical markers of cardiovascular diseases and a toxicologic study in which animals were exposed to mixtures of vehicle engine emissions and non-vehicular PM and analyzed for vascular effects. Section 3 contains an integrated discussion of the studies. This report, along with Research Report 177 (Lippmann et al.), is one of HEI's National Particle Component Toxicity (NPACT) studies, which describe the most systematic multidisciplinary studies to date to investigate the health effects of PM components in humans and animal models at locations across the United States where the effects of PM sources and components may differ. The report includes a Commentary and a Synthesis by the NPACT Review Panel.

Newsletter
Health Effects Institute
July 2013

Contents: Annual Conference Showcases HEI's Scientific Program; Did the Irish Coal Bans Improve Air Quality and Health? Novel Approaches to Analyzing Health Effects Data; Board Seeks New Review Committee Chair; HEI Moving to Improve the Way it Communicates; Expert Group Conducts Peer Review of ACES Pathology Results

Newsletter
Health Effects Institute
May 2013

This newsletter reports on an expert panel named to review diesel epidemiology studies, two HEI Asia workshops on the global health impact of air pollution, and a meeting of HEI's Research Committee and sponsors reviewing progress and priorities, as well as HEI in the news.

Newsletter
Health Effects Institute
February 2013

Contents: Review of Ultrafine Particles Examines Wide Range of Health Studies; Timely Topics, Great City Highlight HEI Annual Conference; Tool Helps Identify Nanoparticles from Motor Vehicles; Air Pollution Controls During 2008 Beijing Olympics; Science Workshop to Inform European Union Policies; Study Finds Ambient Air Pollution Among Top Global Health Risks; ACES Emissions Testing and Animal Exposures Now Complete

Newsletter
Health Effects Institute
November 2012

This update describes a new Diesel Epidemiology Project; a call for Research Proposals: Improving Traffic Exposure Analysis for Health Studies; the Advanced Collaborative Emissions Study nearing completion; a new member of the Research Committee; a visit from Japanese Auto Officials; and two new Research Reports on Potential Air Toxics Hot Spots in Truck Terminals and Cabs and on the Impact of 1990 Hong Kong Limits on Sulfur Content in Fuel. 

Research Report 166
Jacob D McDonald
Jeffrey C Bemis
Lance M Hallberg
Daniel J Conklin
Maiying Kong
September 2012

This report provides the first systematic look at the health effects of exposures to emissions from a new-technology heavy-duty diesel engine. Included in this report are results obtained in rats and mice exposed for 1 and 3 months (and some results in rats at 12 months) to exhaust from a 2007-compliant diesel engine with aftertreatment to reduce particulate matter concentrations. Part 1 describes the core inhalation study by Drs. Jake McDonald and Joe Mauderly of the Lovelace Respiratory Research Institute, with results on general organ toxicity, lung histopathology, pulmonary function, and markers of inflammation and oxidative stress in blood and lung lavage fluid. Parts 2 and 3 describe studies by Drs. Jeffrey Bemis of Litron Laboratories and Lance Hallberg of the University of Texas Medical Branch, respectively, assessing genotoxic endpoints in the exposed rodents. Part 4 describes a study of vascular markers by Daniel Conklin of the University of Louisville. The Preface to this report contains background information about the planning and designing of the study, including decisions regarding the diesel exhaust dilutions and the choice of rodent strains.

Contents: HEI research contributes to international (IARC) review of diesel and gasoline cancer risk; Annual Conference highlights new PM, diesel, and ozone findings, major issues; Air quality outcomes of national limits on power plant emissions; Study tests potential uses of satellite-based PM measurements.

Contents: Greenbaum Testifies on "Producing Credible Science for Decisions"; New HEI Health Effects Study of Modern Diesel Engine Emissions; Health Outcomes and Biomarkers Studies Approved; Multicity Study in Latin America; Air Pollution and Children's Health in Vietnam; HEI in the News; Communication 17: ACES Exposure Atmosphere; Annual Report Now Available; New Global Burden of Disease Estimates; HEI Investigator Wins Haagen-Smit Prize; Workshop on Assessing Exposure to Pollution from Traffic; IARC Review of Diesel and Gasoline Exhaust
Communication 17
Joe L Mauderly
Jacob D McDonald
February 2012
Communication 17 describes Phase 3A of the Advanced Collaborative Emissions Study (ACES) to test emissions and health effects of emissions from 2007- and 2010-compliant diesel engines. The Communication contains results from the characterization of exposure atmospheres by Drs. Joe Mauderly and Jake McDonald at the Lovelace Respiratory Research Institute in advance of the start of animal toxicity testing in ACES Phase 3B. It provides important background information on the emissions from one selected 2007-compliant engine and their concentrations in the animal exposure chambers.

Contents: Effects of Exposure to Diesel Exhaust Particles in Persons with Asthma and Allergy; Workshop Brings Experts Together: Atmospheric Chemists and Health Effects Scientists Meet at HEI to Discuss Common Goals; Symposium Sheds Light on Air Toxics Hot Spots; Wood Stove Changeout Program Brings Some Improvements in Health, Air Quality; Three New HEI Studies Launched: Ozone Exposure and Inflammatory Cells / PM Exposure and Heart Rhythm / Impact of Exposure in Early Life; ACES Reaches Important Milestones; New Investigator Awards Announced; Eaton Elected to Institute of Medicine