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Update Fall 2017

Health Effects Institute
October 2017

In this issue of HEI Update, read about the new ways HEI is making study data accessible; a literature review that HEI will soon initiate on the effects of exposure to traffic-related air pollution; two new members of the HEI Review Committee; and a newly published summary of an HEI expert workshop on the effects of fuel composition on particulate matter emissions.

Particulate Air Pollutants, Brain Structure, and Neurocognitive Disorders in Older Women

Jiu-Chiuan Chen
Xinhui Wang
Marc Serre
Steven Cen
Meredith Franklin
Mark Espeland
October 2017
Research Report 193

Research Report 193 describes a novel study by Jiu-Chiuan Chen and colleagues examining possible associations between long-term exposure to ambient particulate matter (PM) and changes in the brains of older women in the United States. The study focused on brain volumes and neurocognitive outcomes, specifically mild cognitive impairment and dementia. Dr. Chen used neuroimaging and cognitive outcome data from women enrolled in the Women’s Health Initiative Memory Study and estimated their exposure to ambient PM2.5 and to diesel PM.

Update Summer 2017

Health Effects Institute
August 2017

In this issue of HEI Update, read about the Haagen-Smit Clean Air Leadership Award given to HEI President Dan Greenbaum by the California Air Resources Board, the two 2017 recipients of HEI’s Walter A. Rosenblith New Investigator Award, and the progress of HEI studies examining potential health effects at low levels of air pollution. Also in this issue is a recap of HEI’s recent Annual Conference in Alexandria, Virginia.

Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes

Mark W Frampton
John R Balmes
Philip A Bromberg
Paul Stark
Mehrdad Arjomandi
Milan J Hazucha
David Q Rich
Danielle Hollenbeck-Pringle
Nicholas Dagincourt
Neil Alexis
Peter Ganz
Wojciech Zareba
Maria G Costantini
June 2017
Research Report 192 Part 1

HEI Research Report 192 describes a multicenter study by John Balmes at the University of California–San Francisco, Phil Bromberg at the University of North Carolina–Chapel Hill, and Mark Frampton at the University of Rochester, New York. The study was designed to test whether ozone has short-term cardiovascular effects at present-day ambient levels. It evaluated respiratory and cardiovascular outcomes in 87 healthy participants (60 years old on average) who were exposed to 0, 70, or 120 ppb ozone for 3 hours while exercising moderately.