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Mechanisms of Particulate Matter Toxicity in Neonatal and Young Adult Rat Lungs

Research Report 135,
2008

Research Report 135 describes a study to determine whether the biologic response to inhaled ultrafine particles depends on particle composition. Neonatal and young adult rats were exposed to laboratory-generated ultrafine metal particles, either alone or in combination with soot, and their lungs examined for oxidative stress, inflammation, and injury.