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Assessing Adverse Health Effects of Long-Term Exposure to Low Levels of Ambient Air Pollution: Implementation of Causal Inference Methods

Research Report 211,
2022

Research Report 211, available for downloading below, presents a major HEI study examining the risk of mortality associated with exposure to low ambient air pollution concentrations in a cohort of 68.5 million older Americans. 

Dr. Francesca Dominici of the Harvard T.H. Chan School of Public Health and colleagues developed annual exposure models at a spatial resolution of 1 km × 1 km for the years 2000 to 2016 covering the contiguous United States for fine particulate matter (PM2.5), nitrogen dioxide (NO2), and ozone (O3). 

The study is one of three funded as part of RFA 14-3, Assessing Health Effects of Long-Term Exposure to Low Levels of Ambient Air Pollution, issued in 2014. The studies, based in the United States, Canada, and Europe, incorporated state-of-the-art exposure methods and large cohorts in high-income countries. 

This U.S. report follows the release of the European study in September 2021. The final Canadian report is expected later in 2022.