Publications

This page is a list of publications in reverse chronological order. Please use search or the filters to browse by research areas, publication types, and content types.

Displaying 151 - 160 of 341. Show 10 | 25 | 50 | 100 results per page.

Effects of Long-Term Exposure to Traffic-Related Air Pollution on Respiratory and Cardiovascular Mortality in the Netherlands: The NLCS-AIR Study

Bert Brunekreef
Rob Beelen
Gerard Hoek
Leo Schouten
Sandra Bausch-Goldbohm
Paul Fischer
Ben Armstrong
Edward Hughes
Piet van den Brandt
2009
Research Report 139
Multipollutant Mixtures
Nitrogen Oxides
Particulate Matter
Global Health

Research Report 139 describes a study in the Netherlands using data from the ongoing Netherlands Cohort Study (NLCS) on diet and cancer. The study is one of the first to systematically assess longer term exposure and mortality in a well characterized European population; it followed a pilot study of 5000 adults randomly selected from the NLCS cohort conducted by the same team of investigators. For the current study, Dr.

The Influence of Improved Air Quality on Mortality Risks in Erfurt, Germany

Annette Peters
Susanne Breitner
Josef Cyrys
Matthias Stölzel
Mike Pitz
Gabriele Wölke
Joachim Heinrich
Wolfgang Kreyling
Helmut Küchenhoff
H-Erich Wichmann
2009
Research Report 137
Accountability
Global Health

Research Report 137, The Influence of Improved Air Quality on Mortality Risks in Erfurt, Germany, is the first study to come out of HEI's program on the health impact of regulatory and other actions to improve air quality, known as accountability. The report describes sweeping changes in the economy and energy use that occurred in the former East Germany after the 1990 reunification as a result of stricter environmental controls and modernization of industry, transportation, and household heating. Dr.

Health Effects of Real-World Exposure to Diesel Exhaust in Persons with Asthma

Junfeng (Jim) Zhang
James E McCreanor
Paul Cullinan
Kian Fan Chung
Pamela Ohman-Strickland
In-Kyu Han
Lars Järup
Mark J Nieuwenhuijsen
2009
Research Report 138
Diesel Exhaust
Particulate Matter
Global Health

Research Report 138, Health Effects of Real-World Exposure to Diesel Exhaust in Persons with Asthma, is one part of HEI's larger program on the role of particles in exacerbating asthma and other allergic diseases. This report describes a study to evaluate how inhaling air with a high concentration of diesel exhaust from vehicular traffic while walking on a busy street in Central London might affect people who had either mild or moderate asthma. Dr.

Uptake and Inflammatory Effects of Nanoparticles in a Human Vascular Endothelial Cell Line

Ian M Kennedy
Dennis Wilson
Abdul I Barakat
2009
Research Report 136
Particulate Matter

Research Report 136, Uptake and Inflammatory Effects of Nanoparticles in a Human Vascular Endothelial Cell Line, is one part of HEI's larger program on the health effects of particulate matter and its various components. This report describes a one-year study to evaluate which physicochemical characteristics of metal nanoparticles may contribute to their toxicity.

Mechanisms of Particulate Matter Toxicity in Neonatal and Young Adult Rat Lungs

Kent E Pinkerton
Yamei Zhou
Caiyun Zhong
Kevin R Smith
Stephen V Teague
Ian M Kennedy
Margaret G Ménache
2008
Research Report 135
Particulate Matter

Research Report 135 describes a study to determine whether the biologic response to inhaled ultrafine particles depends on particle composition. Neonatal and young adult rats were exposed to laboratory-generated ultrafine metal particles, either alone or in combination with soot, and their lungs examined for oxidative stress, inflammation, and injury.

Public Health and Air Pollution in Asia (PAPA): Key Results from Bangkok, Hong Kong, Shanghai, and Wuhan

Health Effects Institute
2008
Communication 13
Global Health
Ozone & Oxidants
Particulate Matter

The September issue of Environmental Health Perspectives published the first systematic presentation of the HEI-funded PAPA studies in Bangkok, Hong Kong, Shanghai, and Wuhan, as well as a combined analysis and accompanying editorial. These articles have been reprinted and are currently available as HEI Communication 13. The detailed studies and accompanying HEI commentaries will be published by the Institute this spring.

Black-Pigmented Material in Airway Macrophages from Healthy Children: Association with Lung Function and Modeled PM10

Jonathan Grigg
Neeta Kulkarni
Nevil Pierse
Lesley Rushton
Christopher O'Callaghan
Andrew Rutman
2008
Research Report 134
Particulate Matter
Global Health

Research Report 134 describes a study that evaluated whether there was an association between particles detectable in the airways of healthy children and a) estimates of local, traffic-derived PM10 at the children's home addresses or b) their lung function. Dr. Jonathan Grigg and colleagues recruited 116 healthy children aged 8 to 15 years who lived in Leicester, UK. In addition to modeling each child's exposure, the investigators measured lung function and evaluated induced sputum for particles in airway macrophages and markers of inflammation.

Mobile-Source Air Toxics: A Critical Review of the Literature on Exposure and Health Effects

Health Effects Institute
2007
Special Report 16
Air Toxics

A Special Report of the Institute's Air Toxics Review Panel. Special Report 16 summarizes the health effects of exposure to the 21 mobile-source air toxics (MSATs) defined by the 2001 EPA mobile-source rulemaking and critically analyzes the literature for a subset of seven MSATs (acetaldehyde, acrolein, benzene, 1,3-butadiene, formaldehyde, naphthalene, and polycyclic organic matter). The report also assesses and summarizes research gaps and unresolved questions, as understood in the context of the current regulatory agenda. The report focuses on MSATs for which mobile sources are a sizable source of human exposure and for which existing data suggest that health effects might be observed at concentrations approaching those found in ambient air. For each MSAT, the following questions are addressed: (1) To what extent are mobile sources a significant source of exposure to this MSAT? (2) Does this MSAT affect human health? (3) Does this MSAT affect human health at environmental conditions?

Relationships of Indoor, Outdoor, and Personal Air (RIOPA). Part II. Analyses of Concentrations of Particulate Matter Species

Barbara J Turpin
Clifford P Weisel
Maria T Morandi
Steven Colome
Thomas Stock
Steven Eisenreich
Brian Buckley
et al
2007
Research Report 130-II
Air Toxics

The RIOPA project comprised three studies, one funded by the Mickey Leland National Urban Air Toxics Research Center (NUATRC) and two funded by HEI, that investigated seasonal concentrations of 16 VOCs, 10 carbonyls, and PM2.5 in homes in Los Angeles CA, Houston TX, and Elizabeth NJ. The project was jointly funded and reviewed by a Special Review Panel of the two organizations. It generated a rich database on concentrations of air toxics and PM2.5 in the personal breathing zone of 100 adults in each city as well as inside and outside their homes.

Internet-Based Health and Air Pollution Surveillance System

Scott L Zeger
Aidan McDermott
Francesca Dominici
Roger D. Peng
Jonathan Samet
2006
Communication 12
Air Pollution
Particulate Matter
Innovation
Statistical Methods

HEI Communication 12 describes a project by Dr Scott Zeger and colleagues at the Johns Hopkins Bloomberg School of Public Health that was funded by HEI to make data and software from the National Morbidity, Mortality, and Air Pollution Study (NMMAPS) available to the wider research and policy communities. This Communication contains the Project Report, which describes the Internet-Based Health and Air Pollution Surveillance System (iHAPSS), along with Comments from some members of the HEI Health Research and Review Committees and other experts who had used the data.