This page is a list of publications in reverse chronological order. Please use search or the filters to browse by research areas, publication types, and content types.

Displaying 41 - 50 of 294. Show 10 | 25 | 50 | 100 results per page.

Advanced Collaborative Emissions Study (ACES): Lifetime Cancer and Non-Cancer Assessment in Rats Exposed to New-Technology Diesel Exhaust

Jacob D McDonald
Jeffrey C Bemis
Lance M Hallberg
Daniel J Conklin
January 2015
Research Report 184

This report describes four studies conducted as a single phase (Phase 3B) of HEI's Advanced Collaborative Emissions Study (ACES) program, which was designed to evaluate the emissions and health changes resulting from substantially improved diesel engines required under the U.S. EPA 2007–2010 Heavy Duty Diesel Rule. These studies were conducted by Drs. Jacob D. McDonald of the Lovelace Respiratory Research Institute, Albuquerque, New Mexico, Jeffrey C. Bemis of Litron Laboratories, Rochester, New York, Lance M. Hallberg of the University of Texas Medical Branch, Galveston, Texas, and Daniel J. Conklin, University of Louisville, Kentucky.

Synergistic Effects of Particulate Matter and Substrate Stiffness on Epithelial-to-Mesenchymal Transition

Thomas H Barker
Marilyn M Dysart
Ashley C Brown
Alison M Douglas
Vincent F Fiore
Armistead (Ted) G Russell
November 2014
Research Report 182

This report is a study focused on lung tissue repair processes after inflammation and injury resulting from exposure to particulate matter (PM) from combustion sources. Dr. Thomas H. Barker of Georgia Institute of Technology, a recipient of HEI's Walter A. Rosenblith New Investigator Award, and his colleagues tested the hypotheses that alveolar epithelial cells grown on substrates of increasing stiffness would transition to mesenchymal cells — an early step along the pathway to fibrosis — and that the addition of fine PM would enhance these effects.

Update Fall 2014

Health Effects Institute
October 2014

Contents: Setting a Course for 2020: The HEI Strategic Plan; RFA Seeks New Epidemiologic Studies; HEI Launches New International Project // Group of Experts Will Estimate Global Burden of Disease from Specific Major Air Pollution Sources; Communicating Results of Research; How PM May Affect Epithelial Cell Differentiation; Progress on Major Ozone Study; Panel Tours Gas Well Sites

Update Summer 2014

Health Effects Institute
August 2014

Contents: Conference Eyes Future of Air Pollution Research, Policy; Leading Health Expert to Chair Review Committee; Workshop on Unconventional Oil and Gas Development; Developing New Models for Ultrafine Particles and Air Toxics Exposures; Sharing Insight from NPACT Setting Research Priorities (Research Planning Meeting); HEI in the News; HEI Strategic Plan 2015-2020 Taking Shape

Development and Application of an Aerosol Screening Model for Size-Resolved Urban Aerosols

Charles O Stanier
Sang-Rin Lee
June 2014
Research Report 179

This report describes a study in which a model to simulate the dispersion of ultrafine particles near roadways was developed and tested. Understanding what happens to ultrafines near roadways – and how that influences exposure – is a key area that HEI's Perspectives 3 on ultrafines (2013) identified. Dr. Charles Stanier at the University of Iowa–Iowa City, a recipient of HEI's Walter A.

Personal Exposure to Mixtures of Volatile Organic Compounds: Modeling and Further Analysis of the RIOPA Data

Stuart Batterman
Feng-Chiao Su
Shi Li
Bhramar Mukherjee
Chunrong Jia
June 2014
Research Report 181

This report describes a study to identify factors that influence exposure to volatile organic compounds (VOCs) and VOC mixtures. Dr. Stuart Batterman at the University of Michigan–Ann Arbor and colleagues used the extensive data that HEI posted on the Web from the Relationships of Indoor, Outdoor, and Personal Air (RIOPA) study (HEI Research Report 130 Parts I and II), and data from the National Health and Nutrition Examination Survey (NHANES), to characterize exposure distributions for 15 VOCs, with an emphasis on high concentrations. Factors examined included geographic location, weather, characteristics of participants' homes, and specific activities, such as pumping gas.

Update Spring 2014

Health Effects Institute
May 2014

Contents: HEI Research Committee Welcomes a New Epidemiologist; Ultrafine Particles Study Focuses on School Buses; New Initiative Addresses Unconventional Oil and Gas Development; A Growing Audience for HEI's Web Site; Sponsors, Research Committee Meet in Boston;  Assessing Diesel Epidemiology Studies; Walter A. Rosenblith New Investigator Award

Characterizing Ultrafine Particles and Other Air Pollutants In and Around School Buses

Yifang Zhu
Qunfang Zhang
March 2014
Research Report 180

This report describes a study that assessed levels of ultrafine particles and other pollutants around diesel engine school buses and identified factors contributing to those levels. Dr. Yifang Zhu at the University of California–Los Angeles, a recipient of HEI's Walter A. Rosenblith New Investigator Award, measured pollutant levels in and around school buses while driving, while idling, before and after retrofitting with a diesel particle filter and/or oxidation catalyst, and before and after installing an in-cabin filtration system.

Update Winter 2014

Health Effects Institute
February 2014

Contents: ACES Phase 2 Study Shows Dramatic Reductions in Emissions from Newer Diesel Engines; Annual Conference in D.C. Area Will Spotlight Science to Inform the Future; HEI Hosts Diesel Epidemiology Workshop; Making Data on Air Pollution and Health Accessible;  New Funding Opportunities: Traffic Related Exposure Studies / HEI Seeks Research on Non-Tailpipe and Tailpipe Emissions Near Urban Roads and in Tunnels; Window on Tomorrow: Building the HEI Strategic Plan 2015–2020

New Statistical Approaches to Semiparametric Regression with Application to Air Pollution Research

James M Robins
Peng Zhang
Rajeev Ayyagari
Roger Logan
Eric Tchetgen Tchetgen
Lingling Li
Thomas Lumley
Aad van der Vaart
November 2013
Research Report 175

This report describes semiparametric methods for epidemiologic investigations of the short-term effects of air pollution on health, intended specifically to improve the reliability of point estimates and confidence intervals. Dr. James Robins of the Harvard School of Public Health and colleagues developed the new methods, used simulations to compare them with other methods, and applied them to a large epidemiologic data set from the National Morbidity, Mortality, and Air Pollution Study (NMMAPS) to assess their effectiveness. The report is accompanied by a short editorial to assist the reader in understanding this study and its contributions to epidemiologic methods for air pollution.