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RFA 21-1 Quantifying Real-World Impacts of Non-Tailpipe Particulate Matter Emissions

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RFA 21-1

Request for Applications 21-1 solicits applications to develop, evaluate, and apply real-world exposure indicators of non-tailpipe PM emissions from motor vehicles (e.g., from tire, brake, wheel weights, and road wear and resuspension of dust from the road surface) and to assess the impacts of such emissions on air quality, human exposure, and human health.


The approaches of interest include:

  • Identifying and validating exposure indicators to characterize non-tailpipe PM emissions in near-road or ambient air.
  • Developing or extending existing approaches to measure or non-tailpipe PM in the near-road environment.
  • Estimating current and future potential impacts of non-tailpipe emissions from passenger and/or commercial vehicles on air quality, exposure, and/or potential contribution of non-tailpipe emissions to health burden attributable to ambient PM2.5 mass.
RFA 21-1: Quantifying Real-World Impacts of Non-Tailpipe Particulate Matter Emissions provides funding for up to 3 studies with a funding cap of $800,000 each. A total of up to $2.5 million will be available for this program.
How to Apply

*** Please consult the Frequently Asked Questions before contacting HEI staff. Thank you! ***


Applicants should submit a Preliminary Application using the form provided, and describe the title, scientific rationale, study aims, study design and approach, statistical methods, and anticipated results in 4 pages. Preliminary applications should be submitted by email in PDF format to (subject line: PI last name RFA 21-1 Preliminary Application) no later than JANUARY 19, 2022. HEI will acknowledge receipt of the application. Applicants will be informed whether or not to submit a full application after the Research Committee meeting in March 2022.

For details check out the application instructions.


Investigators invited to submit a Full Application should use forms F‐1 to F‐12 and consult the Instructions for Completing the Application. Note that there is a separate set of forms for this Award; Form F-12 is optional. Please note that the required font size is 11-point with 1-inch margins, single-spaced. The application forms should be turned into a PDF with appropriate bookmarks before submitting. Please check our website for updates.

Full applications for RFA 21-1 (by invitation only) should be submitted to (subject line: PI last name RFA 21-1 Full Application) no later than MAY 25, 2022. HEI will acknowledge receipt of the application. Applicants will be notified of the funding decision after discussion by the Research Committee in July 2022 .

Applicant Webinar Info

October 19, 2021, 10:00 am to 11:00 am
HEI hosted a webinar to provide information on the goals of this RFA and how to apply. There was time for potential applicants to ask questions of members of the HEI Research Committee and staff. The webinar slides and a summary of the Q&A are available below.

Allison P. Patton

Preliminary Application Due Date: 
January 19, 2022
Full Application Due Date: 
May 25, 2022

Ongoing studies funded under this RFA

Queen Mary University of London, United Kingdom

In this study, participants with mild to moderate asthma will ride stationary bicycles on sidewalks in three London, UK environments (busy road characterized by stop-and-go traffic, high speed continuous traffic, and urban background) to measure how exposure to traffic with different mixtures of non-tailpipe and tailpipe emissions affects lung function of asthmatic adults.

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University of Toronto, Canada

This study will measure concentrations of non-tailpipe particulate matter across Toronto, Canada to determine how much non-tailpipe pollution people might breathe in everyday life and how to better measure these exposures in the future.

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