Publications

This page is a list of publications in reverse chronological order. Please use search or the filters to browse by research areas, publication types, and content types.

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Update Summer 2012

Health Effects Institute
July 2012
Newsletter

Contents: HEI research contributes to international (IARC) review of diesel and gasoline cancer risk; Annual Conference highlights new PM, diesel, and ozone findings, major issues; Air quality outcomes of national limits on power plant emissions; Study tests potential uses of satellite-based PM measurements.

Effects of Short-Term Exposure to Air Pollution on Hospital Admissions of Young Children for Acute Lower Respiratory Infections in Ho Chi Minh City, Vietnam

HEI Collaborative Working Group on Air Pollution, Poverty, and Health in Ho Chi Minh City
June 2012
Research Report 169

This report describes a study to investigate the relationships among daily variations in air pollution in Ho Chi Minh City (HCMC), Vietnam, hospital admissions for acute lower respiratory infections in children under age 5, and poverty. The study was part of HEI's Public Health and Air Pollution in Asia (PAPA) program and is the first study of air quality and health to be performed in Vietnam. The team of investigators, led by Drs. Le Truong Giang, Long Ngo, and Sumi Mehta, collected daily pollutant data for PM10, sulfur dioxide, nitrogen dioxide, and ozone at multiple locations throughout the city and obtained admissions data from the two pediatric hospitals in HCMC. They then performed statistical analysis on the data using Poisson time-series and case–crossover methods.

Assessment and Statistical Modeling of the Relationship Between Remotely Sensed Aerosol Optical Depth and PM2.5 in the Eastern United States

Christopher J Paciorek
Yang Liu
May 2012
Research Report 167

This report describes a study to assess the ability of satellite-based measurements from National Aeronautics and Space Administration (NASA) satellites to fill spatial and temporal gaps in existing monitoring networks in the eastern United States. Dr. Paciorek and colleagues developed statistical models for integrating monitoring, satellite, and geographic information system (GIS) data to estimate monthly ambient PM2.5 concentrations and used those models to estimate monthly average PM2.5 concentrations across the eastern United States. They then developed and applied statistical methods to quantify how uncertainties in exposure estimates based on ground-level monitoring data might be reduced. This study was funded under the Walter A. Rosenblith New Investigator Award.

Update Spring 2012

Health Effects Institute
April 2012
Newsletter
Contents: Greenbaum Testifies on "Producing Credible Science for Decisions"; New HEI Health Effects Study of Modern Diesel Engine Emissions; Health Outcomes and Biomarkers Studies Approved; Multicity Study in Latin America; Air Pollution and Children's Health in Vietnam; HEI in the News; Communication 17: ACES Exposure Atmosphere; Annual Report Now Available; New Global Burden of Disease Estimates; HEI Investigator Wins Haagen-Smit Prize; Workshop on Assessing Exposure to Pollution from Traffic; IARC Review of Diesel and Gasoline Exhaust

Allergic Inflammation in the Human Lower Respiratory Tract Affected by Exposure to Diesel Exhaust

Marc A Riedl
David Diaz-Sanchez
William S Linn
Henry Gong Jr
Kenneth W Clark
Richard M Effros
J Wayne Miller
David R Cocker
Kiros T Berhane
February 2012
Research Report 165

This report describes a study evaluating the effects of exposure to diesel exhaust (DE) and nitrogen dioxide (NO2) on the lower airways and blood of allergic asthmatic participants. The study by Dr. Riedl and colleagues was funded as part of HEI's research program looking at diesel exhaust and other particle exposures and allergic response. The participants were exposed in random order to 100 µg/m3 diesel exhaust or 0.35 ppm nitrogen dioxide for 2 hours, with or without an allergen inhalation challenge. The investigators measured multiple physiologic and pulmonary function endpoints, including specific airway resistance, oxygen saturation, bronchial reactivity, and inflammatory and immunologic endpoints.

Advanced Collaborative Emissions Study (ACES) Phase 3A: Characterization of U.S. 2007-Compliant Diesel Engine and Exposure System Operation

Joe L Mauderly
Jacob D McDonald
February 2012
Communication 17
Communication 17 describes Phase 3A of the Advanced Collaborative Emissions Study (ACES) to test emissions and health effects of emissions from 2007- and 2010-compliant diesel engines. The Communication contains results from the characterization of exposure atmospheres by Drs. Joe Mauderly and Jake McDonald at the Lovelace Respiratory Research Institute in advance of the start of animal toxicity testing in ACES Phase 3B. It provides important background information on the emissions from one selected 2007-compliant engine and their concentrations in the animal exposure chambers.

Assessment of the Health Impacts of Particulate Matter Characteristics

Michelle L Bell
January 2012
Research Report 161

This report describes a study by Dr. Michelle Bell of Yale University to evaluate the effects of exposure to components of the PM2.5 mixture on short-term morbidity and mortality, using data on 52 components of PM2.5 for 187 US counties. The report explores regional and seasonal variation in the chemical composition of PM2.5 and whether this variation affects the association between short-term exposure to PM and health effects. This study was funded under the Walter A. Rosenblith New Investigator Award.

Update Winter 2012

Health Effects Institute
January 2012
Newsletter

Contents: Effects of Exposure to Diesel Exhaust Particles in Persons with Asthma and Allergy; Workshop Brings Experts Together: Atmospheric Chemists and Health Effects Scientists Meet at HEI to Discuss Common Goals; Symposium Sheds Light on Air Toxics Hot Spots; Wood Stove Changeout Program Brings Some Improvements in Health, Air Quality; Three New HEI Studies Launched: Ozone Exposure and Inflammatory Cells / PM Exposure and Heart Rhythm / Impact of Exposure in Early Life; ACES Reaches Important Milestones; New Investigator Awards Announced; Eaton Elected to Institute of Medicine

Pulmonary Particulate Matter and Systemic Microvascular Dysfunction

Timothy R Nurkiewicz
Dale W Porter
Ann F Hubbs
Samuel Stone
Amy M Moseley
Jared L Cumpston
Adam G Goodwill
Stephanie J Frisbee
Peter L Perrotta
Robert W Brock
Jefferson C Frisbee
Matthew A Boegehold
David G Frazer
Bean T Chen
Vincent Castranova
December 2011
Research Report 164

This report describes a study that evaluated whether exposure to fine or nano-titanium dioxide (TiO2) particles may affect cardiovascular endpoints, in particular endothelium-dependent vascular dilation. Dr. Nurkiewicz and colleagues exposed rats via inhalation to 0.5 to 20 mg/m3 TiO2 for up to 12 hours and evaluated them for vascular dilation and for markers of oxidative stress, coagulation, and inflammation. This study was funded under the Walter A. Rosenblith New Investigator Award.   

Assessing the Impact of a Wood Stove Replacement Program on Air Quality and Children’s Health

Curtis W Noonan
Tony J Ward
William Navidi
Lianne Sheppard
Megan Bergauff
Chris Palmer
December 2011
Research Report 162
This report describes a study evaluating a community-wide program to improve air quality in a rural mountain community (Libby, Montana) by replacing older, more polluting wood stoves with new, less polluting stoves. Over the course of 4 winters, Dr. Noonan and colleagues measured PM2.5 and markers for wood smoke outdoors, in schools, and in about 20 homes before and after stove changeout. In parallel, they tracked children's respiratory symptoms (based on parental surveys) and school absences.