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The Health Effects Institute

What's New?

This is where we will announce the most recent additions to our web site. If you have visited us before and want to know what has changed, take a look here first.

HEI Annual Conference 2015

May 3-5, 2015, Philadelphia, PA
Click here for more information
Photo Courtesy of B. Krist, Visit Philadelphia

HEI report on lifetime animal exposure to new-technology diesel engine exhaust finds no evidence of lung cancer – January 2015 NEW
Research Report 184, Advanced Collaborative Emissions Study (ACES): Lifetime Cancer and Non-Cancer Assessment in Rats Exposed to New-Technology Diesel Exhaust, describes the first study to conduct a comprehensive evaluation of lifetime exposure to new-technology diesel exhaust (NTDE). The study was conducted by Drs. Jacob McDonald of the Lovelace Respiratory Research Institute, Jeffrey Bemis of Litron Laboratories, Lance Hallberg of the University of Texas Medical Branch, and Daniel Conklin of the University of Louisville, and their colleagues. Male and female rats were exposed for 80 hours per week, for up to 30 months, to emissions from a heavy-duty diesel engine meeting stringent 2007 U.S. standards that has greatly reduced particle emissions compared with pre-2007 engines. The investigators evaluated more than 100 different biologic endpoints, including tumor development, and compared the results with biologic effects seen in earlier studies in rats exposed to diesel exhaust from pre-2007 engines. For a Press Release, click here PDF. To download HEI Research Report 184, including a Commentary by the HEI ACES Review Panel, click here.

HEI issues Fall 2014 Research Agenda – December 2014
The Fall 2014 Research Agenda is now available, which includes Request for Applications (RFA) 14-3, Assessing Health Effects of Long-term Exposure to Low Levels of Ambient Air Pollution, and RFA 14-4, Walter A. Rosenbltih New Investigator Award. For more information visit our Funding page. To download the Fall 2014 RFA booklet, click here PDF.

HEI publishes report on mechanisms of lung tissue repair after PM exposure – November 2014
Research Report 182, Synergistic Effects of Particulate Matter and Substrate Stiffness on Epithelial-to-Mesenchymal Transition, is a study focused on lung tissue repair processes after inflammation and injury resulting from exposure to particulate matter (PM) from combustion sources. Dr. Thomas H. Barker of Georgia Institute of Technology, a recipient of HEI’s Walter A. Rosenblith New Investigator Award, and his colleagues tested the hypotheses that alveolar epithelial cells grown on substrates of increasing stiffness would transition to mesenchymal cells — an early step along the pathway to fibrosis — and that the addition of fine PM would enhance these effects. To download HEI Research Report 182, including a Critique by the HEI Health Review Committee, click here.

HEI seeks comments on revised Strategic Plan 2015-2020 – October 2014
After releasing a draft Strategic Plan for the period 2015 through 2020 in April 2014, HEI has received valuable feedback from its stakeholders, scientific committees, and the broader scientific community. HEI is now seeking input on its revised Strategic Plan PDF before finalizing it. Please send your suggestions to Dan Greenbaum or Rashid Shaikh by November 15, 2014.

HEI Fall Update now available – October 2014
The Fall 2014 Update newsletter features the HEI Strategic Plan 2015-2020, which outlines HEI's course for the next 5-year period and beyond; an upcoming RFA seeking new epidemiologic studies at low concentrations of ambient air pollution; and progress on HEI's multicenter ozone study. The newsletter also features HEI's launch of a new international project on the global burden of disease from specific major air pollution sources. To download the newsletter, click here.

HEI announces Special Committee on Unconventional Oil and Gas Development – May 2014
There is a growing need to improve understanding of the potential health and environmental impacts of unconventional oil and gas development. In response to this need, and with support from a number of foundations in the Appalachian region, HEI has convened a committee of experts to develop a strategic plan to guide future research. This HEI initiative is designed to summarize, by late 2014, what is known about the potential human health, ecologic, environmental, and social effects of unconventional oil and gas development in the Appalachian Basin. By mid-2015, the committee will also develop a strategic plan to guide research aimed at answering key questions at the regional as well as national level. For more information please read the Press Release. PDF For a summary and presentations from the UOG Development Public Workshop, click here.

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Last updated January 29, 2015