The Health Effects Institute
"A Partnership of the U.S. Environmental Protection Agency and Industry"

HEI Annual Conference 2004

Boston, Massachusetts
May 2–4, 2004
Hyatt Regency

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Final Program       Sunday         Monday         Tuesday
Annual Conference Program Book with Abstracts  390 KB

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Presentations available Please click on the speaker's name in the program below to download the presentation.  All files are PowerPoint converted to secure PDF.

Conference Program

Sunday, May 2

12:30    Lunch

1:30      Opening Dan Greenbaum, Health Effects Institute

1:35      Common Science in an Uncommon World: Air Pollution, Health and Regulation in a Global Context

Chairs: Frank Speizer, Harvard Medical School and Chair of the HEI International Scientific Oversight Committee, and Bingheng Chen, Fudan University, Shanghai, China and HEI International Scientific Oversight Committee

The opening session will address air pollution transport and health effects in the United States, Europe, and Asia and will discuss how knowledge gained in one region can benefit understanding globally. The session will highlight current trends in international regulation, the increasing utility of health science in informing decisions, and the implications for future research. HEI’s new review of Asian epidemiologic studies of air pollution and health, with a focus on the daily time-series studies of mortality and morbidity, will be presented. The review was conducted by HEI as part of the Public Health and Air Pollution in Asia (PAPA) Project.

1:35      Global transport of air pollution
Terry Keating, US Environmental Protection Agency ()

2:00      Perspectives on the role of health science in informing international regulation: Challenges and opportunities – a regulatory perspective  
Michael Walsh, Consultant ( 2.9 MB) 

2:25      An industry perspective on the role of health science in supporting international regulation: Challenges and opportunities 
Dennis Schuetzle, The Renewable Energy Institute  ( 370 KB)      

2:50      Break

3:05      HEI’s international program
Robert O’Keefe, Health Effects Institute ( 190 KB)

3:25      Review of Asian epidemiologic research on air pollution and health
Ross Anderson, London University, HEI Review Committee, and HEI International Scientific Oversight Committee  ( 630 KB)

3:45      General discussion

4:00–5:30    Poster Session I     

Posters will present studies funded by HEI and others on exposure and health effects of diesel exhaust and other mixtures and on international single city and multicity epidemiology studies conducted in Europe, North America, and Asia.

6:00      Opening Reception and Dinner

Comments: Career Development Through the Walter A. Rosenblith New Investigator Award
Francesca Dominici, Johns Hopkins University. Dr Dominici is the 1998 recipient of the Walter A. Rosenblith New Investigator Award.

Keynote presentation: Boston’s Big Dig: How Environment and Transportation Merge in the Nation’s Largest Highway and Urban Renewal Project
Frederick Salvucci, Massachusetts Institute of Technology, Center for Transportation and Logistics, and Former Secretary of Transportation and Construction, Commonwealth of Massachusetts

Monday, May 3                                                                Back to top

8:30      Hot Topics! Recent Developments in Air Pollution Research

Chairs: Mark Utell, University of Rochester Medical School and Chair of the HEI Research Committee, and Dan Tosteson, Harvard Medical School and Chair of the HEI Review Committee

This session will present new results from HEI’s research program and current initiatives. First, HEI’s recent study on manganese (used as a fuel additive) will be placed in the context of broader risk assessments. Second, the ACES program on examining emissions and health effects from heavy-duty diesel engines designed to meet the 2007 and 2010 standards will be presented.

8:30      Introduction, Chairs     

8:35      Manganese neurotoxicity       
Roberto Lucchini, University of Brescia, Italy ( 300 KB)

9:00      Alternative tier 2 testing of the fuel additive MMT      
Michael Davis, US Environmental Protection Agency  ( 3.2 MB)

9:25      Discussion       

9:45      Update on the ACES diesel assessment program       
Jane Warren, Health Effects Institute  ( 180 KB)

10:10    Break

10:30–2:00        Poster Session II (with lunch)

Posters will present studies funded by HEI and others on accountability, exposure and health effects of air toxics and particulate matter, and single city and multicity epidemiology studies conducted in Latin America.

Noon–2:00 Lunch

2:00      The Good, the Bad, and the Ugly: Which Particles are Which?

Chairs: John Hoidal, University of Utah and HEI Review Committee, and Rogene Henderson, Lovelace Respiratory Research Institute and HEI Research Committee

This session will focus on health effects of different types of particulate matter. HEI and other organizations have supported related studies in animals and humans that employed particle concentrators in different parts of the United States. Other studies have looked at different sources (eg, wood smoke and diesel or gasoline engine exhaust). The results invite further discussion of how PM size and composition as well as different sources may contribute to health effects. HEI’s plan for a new systematic approach to these questions will be presented.

2:00      Introduction, John Hoidal

2:05      Exposure to diesel exhaust and concentrated ambient particles in allergic rats
Jack Harkema, Michigan State University ( 1.7 MB)

2:30      Comparison of exposure to diesel and gasoline engine exhaust and wood smoke
Joe Mauderly, Lovelace Respiratory Research Institute  ( 970 KB)

2:55      Exploring sources of particle toxicity in different European cities
Henk Bloemen, National Institute for Public Health and Environment (RIVM), the Netherlands  ( 1.4 MB)

3:20      Break

3:40      Allergic and cardiovascular responses to concentrated ambient particle exposure
Michael Kleinman, University of California, Irving  ( 300 KB)

4:05      Assessing toxicity of size-fractionated combustion and ambient air particles
Ian Gilmour, US Environmental Protection Agency  ( 3.4 MB)

4:30      Concluding remarks, Rogene Henderson

4:35      Discussion

4:45      Update on HEI’s new initiative on particulate matter toxicity
Geoffrey Sunshine, Health Effects Institute  ( 160 KB)

5:00      Free Evening

Tuesday, May 4                                                             Back to top

8:30      Living on the Edge: New Approaches in Assessing Exposure

Chairs: Ira Tager, University of California at Berkeley and HEI Research Committee, and Ken Demerjian, State University of New York, Albany and HEI Research Committee

Emerging evidence suggests that air pollution exposure gradients within cities and associated health effects may be larger than previously appreciated. Most previous studies assessed only between-city contrasts. New techniques are now available to aid understanding of exposures at the within-city scale. Recent developments in spatial modeling are being used to increase understanding of how different sources may contribute to personal exposure and health effects. How reliable are these methods and what kinds of data are needed for their validation? Can they help us distinguish health effects of pollutants from different sources? Efforts to measure and model exposure (including geographical information systems and geostatistical interpolation) and their impact on assessment of health effects will be presented and critiqued.

8:30      Introduction, Ira Tager   ( 140 KB)

8:40      Spatial exposure modeling in the new post-structural economy
Michael Jerrett, University of Southern California   ( 1.3 MB)

9:00      Assessing population exposure to motor vehicle emissions
Michael Brauer, University of British Columbia  ( 670 KB)

9:25      Comments
Michael Jerrett

9:50      Break

10:10    Atmospheric chemical transformations: A significant challenge to air pollution exposure modeling
Ken Demerjian   ( 400 KB)

10:45    Measuring and modeling exposure to urban air pollution: Implications for epidemiology studies
Patrick Kinney, Columbia University   ( 100 KB)

11:00    General discussion

 11:30    Lunch

 1:00      Back to the Future: HEI Strategic Plan 2005–2010

Chairs: Dan Greenbaum, Bob O’Keefe and Jane Warren, Health Effects Institute  
( 340 KB)

After a short overview of recent accomplishments, a draft of HEI’s Strategic Plan for 2005 through 2010 will be presented and discussed. Feedback about priorities for HEI research will be welcomed. More information can be found in HEI’s Winter 2004 Update.

3:30      Conference Adjourns

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