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Conference Program       Sunday         Monday         Tuesday

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Conference Program

Sunday, May 4

12:30 pm    Lunch

1:30 pm      Health Impact of Regulations to Improve Air Quality
Chairs: Jonathan Samet, Johns Hopkins Bloomberg School of Public Health and HEI Research Committee, and Daniel Greenbaum, Health Effects Institute

The opening session will summarize the main findings and recommendations of the upcoming HEI monograph on accountability, which explores issues in the design and conduct of research to measure the health impact of regulations and other actions to improve air quality. The session will also cover emerging research on health indicators that can inform accountability efforts as well as new studies funded by HEI.

1:40 pm	What is Accountability? Kenneth Demerjian, State University of New York, Albany and HEI Research Committee
2:00 pm	Why do we care? Daniel Greenbaum
2:20 pm	What are the recent studies in this area? Ross Anderson, London University and HEI Review Committee
2:40 pm	Break
2:55 pm	HEI monograph recommendations Jonathan Samet
3:15 pm	Discussants - Bart Croes, California Air Resources Board - Thomas Burke, Johns Hopkins University (invited) - John Bailar III, University of Chicago and HEI Review Committee
3:55 pm	General discussion

4:10 pm    HEI International Efforts
Robert O'Keefe, Health Effects Institute

In keeping with its Strategic Plan, HEI's efforts are becoming increasingly international in focus, even as it continues its extensive work in the US. This session will summarize HEI's efforts around the world and introduce a new initiative recently launched by HEI, Public Health and Air Pollution in Asia (PAPA), to build better understanding of the effects of air pollution on health in Asia.

4:30 pm    Poster Session I: Accountability and International Research on Air Pollution
Posters will present studies on the Health Impact of Air Pollution Regulation (Accountability), and studies relevant to HEI's international efforts.

6:00 pm    Opening Reception, Dinner, and Keynote Address
Keynote speaker: Dr Donald Kennedy, Editor, Science, and founding member of the HEI Board of Directors


Monday, May 5                                                                Back to top

8:30 am   Mechanisms Underlying Health Effects of Air Pollution: Inflammation
Chairs: Rogene Henderson, Lovelace Respiratory Research Institute and HEI Research Committee, and Stephen Rennard, University of Nebraska Medical Center and HEI Research Committee

The goal of this session is to dicuss a variety of mechanisms by which inhaled pollutants   may cause inflammation.  Presentations will cover reactive oxygen species, inflammation in the lung and elsewhere in the body, and neurogenic inflammation. Understanding the cascade of events within and outside the airways is important for evaluating the health effects of exposure to air pollutants and identifying potential susceptible populations.

8:30 am	Introduction Stephen Rennard
8:35 am	Allergic and non-allergic immune responses in the lung Patricia Finn, Brigham and Women's Hospital
9:00 am	The role of oxidative stress William MacNee, University of Edinburgh, UK
9:25 am	Influence of neurogenic mechanisms on the lung Bradley Undem, Johns Hopkins University
9:50 am	Break
10:20 am	Vascular inflammation: A molecular perspective Kenneth Ramos, University of Louisville Health Sciences Center
10:45 am	Air pollution and inflammation: What do we know? Mark Frampton, University of Rochester
11:15 am	General discussion

11:45 am   Lunch and Poster Session II: Research Funded by HEI and Others
Posters will present ongoing research on the health effects of exposure to air toxics, particulate matter, and diesel exhaust.

3:00 pm    Update on HEI's Current Activities
Jane Warren, Health Effects Institute

3:30 pm    Personal Exposure to Particulate Matter
Chairs: Brian Leaderer, Yale University and HEI Review Committee, and Thomas Louis, Johns Hopkins Bloomberg School of Public Health and HEI Review Committee

The session will be devoted to presentations and discussion on the relation of personal exposure to indoor exposure and ambient measurements of particulate matter in individuals that may be more susceptible to PM (eg, children, the elderly). Most epidemiologic studies of particulate matter have used daily concentrations measured at central monitoring sites as a measure of subjects' exposure. The issue of how measures taken at central monitoring sites can be used as surrogates for personal exposure and the implications for interpreting time-series studies will be discussed.

3:30 pm	Introduction Brian Leaderer
3:40 pm	The relationship between personal exposure to PM and indoor and outdoor levels -  Overview    Michael Brauer, University of British Columbia -  Children and elderly subjects in Boston and Baltimore    Petros Koutrakis, Harvard School of Public Health -  Elderly subjects with cardiovascular disease in Amsterdam and Helsinki    Gerard Hoek, University of Utrecht
4:45 pm	General discussion and questions
5:05 pm	Concluding remarks Thomas Louis

5:15 pm    Free Evening (transport available to Boulder's Pearl Street Mall restaurants)


Tuesday, May 6                                                             Back to top

8:30 am    Air Pollution Time-Series and Cohort Studies: Current Knowledge and Future Directions
Chairs: Ira Tager, University of California at Berkeley and HEI Reseacrh Committee, and Sverre Vedal, National Jewish Medical and Research Center and HEI Review Committee

The goal of this session is to compare and contrast the role of time-series and cohort studies to understanding the health effects of air pollution and contributing to policy decisions. Recent developments in epidemiologic time-series methods, which have led to revised analyses of data on the association between air pollution and mortality, will also be discussed.

8:30 am	Introduction Ira Tager
8:40 am	Reassessment of time-series results Sverre Vedal
9:10 am	Mortality impacts of air pollution from daily time-series and cohort studies: What are they telling us? Francesca Dominici, Johns Hopkins Bloomberg School of Public Health, and 1999 Recipient of the HEI Walter A. Rosenblith New Investigator Award
9:40 am	Break
10:00 am	Uses of mortality impact estimates in the policy realm: Do we have the information we need? Alan Krupnick, Resources for the Future
10:30 am	Discussants - Nino Künzli, University of Southern California - Daniel Krewski, University of Ottawa
11:00 am	General discussion

11:30 am   Conference Adjourns (Lunch Available)

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